Dr. Vatsala Thirumalai

Dr. Vatsala Thirumalai

Education:

B.Tech BiotechnologyAnna UniversityP. GautamLipase catalysis in industrial production
PhDBrandeis UniversityEve MarderUnderstanding motor circuit function in crustacean stomatograstric system

 

Post-doctoral:

Post-doctoralCold Spring Harbour Laboratory, New YorkHollis ClineDevelopment of motor patterns in larval zebrafish
Post-doctoralNational Institue of Health (NIH), BethesdaMichael O’DonovanSynaptic deficits in a mouse model of Spinal Muscular Atrophy
Principal InvestigatorNational Centre for Biological Sciences (NCBS), IndiaNeural Circuits and Development labNeural control of movement during development and in adulthood 

About me:

My lab is interested in understanding the hierarchy, mechanisms and development of neural circuits that generate movement. Our focus is on the development of central pattern generators and the development of descending motor control from the brain. We also seek to understand the mechanisms by which brain locomotor circuits control movement in mature organisms. We use zebrafish, a small fresh water tropical fish endemic to the Ganges, as our model system. We employ a suite of techniques such as whole-cell patch clamp, calcium imaging and light-sheet microscopy to tease out the circuitry responsible for generating swimming in developing and more mature zebrafish. Using these cutting edge tools and technologies, we hope to throw light on the development of neural circuits and the neural basis of locomotion.