Isabelle Mansuy

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University of Zürich and ETH Zürich


Molecular Neuroscience and Neurogenetics

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The purpose of Isabelle Mansuy’s research is to determine the processes underlying the influence of environmental factors on behavior and metabolism across generations using a wide variety of techniques. Her work led to the discovery of molecular suppressors of learning and memory in the adult mouse brain and revealed their role in chromatin remodeling in the adult brain, and in the epigenetic control of memory formation and synaptic plasticity. It also demonstrated their implication in cognitive decline and neurodegeneration. Isabelle Mansuy’s lab is pioneer in the field of transgenerational inheritance.