Hari Prasad Sreekrishnapurath Variyam

Flash talk \ Manfred Eigen lecture theatre Understanding cortical microcircuits and their dynamics is a central goal in cellular neuroscience. Dissociated cortical cultures exhibit a wide range of dynamical repertoires and provide a rich model system for exploring these processes (1). Here, we introduce an experimental setup for directly interfacing with optogenetically modified cell cultures: HD-M.A.N.T.I.S. (High-Density Multielectrode-Array-based Neural Targeting…

Niklas Alvar Laasch

Flash talk \ Manfred Eigen lecture theatre The mammalian cerebral cortex displays a complex network architecture supporting high-level cognition, yet the developmental rules driving its formation remain poorly understood. Current computational models often rely on static templates or global optimization, failing to capture the physical morphogenesis of neural tissue. Here, we present a multi-scale generative model integrating tissue-level mechanics with…

Hannah Zoé Kerger

Flash talk \ Manfred Eigen lecture theatre Understanding the dynamical behaviour of neural networks is a fundamental challenge in neuroscience. Theoretical approaches usually provide complete knowledge of the phase space, facilitating a thorough characterisation of the dynamical system. Characterising experimental systems, however, presents a far greater challenge. Neuronal cultures possess a large number of degrees of freedom, many of which…